Diabetes

 Effect of DXN Products on Diabetes

Maintaining blood sugar levels

Reishi was shown to be able to reduce the blood sugar levels significantly when taken orally as well as evoke a 1 to 4 fold stimulation of insulin secretion from the pancreatic beta cells.

The pancreas is a versatile organ. It is involved in the production of many enzymes as well as hormones that are necessary for digestion. The BETA CELLS of the pancreas are responsible for the production of INSULIN, a hormone that usher glucose into the cells. 

Three species of Reishi have demonstrated their ability to lower glucose levels in the blood as well as increase the beta cells insulin secretion without causing any toxic effect to the various organs.


Malaysian Journal of Science, 26 (2). PP 41-46. Hypoglycaemic, Insulin tropic, and Cytotoxic Activity of Three Species of Ganoderma. Mhd. Saufi Bastami, SitiPauliena Mhd Bohari, WOng Mee Har, Mhd, Noow Wahab, Ariffi Suraya Rahmani, Nor Fadial Rajab, Mhajir Hamid, Malaysia
 

Increase insulin secretion  

Reishi's ability to lower blood sugar levels as well as increase insulin release from the pancreas was seen to be due to the herb's polysaccharides (or complex carbohydrates) that induces the influx of Calcium into the pancreatic cells resulting in the release or secretion of the hormone Insulin.

It has been shown that the entry of Calcium into the BETA CELLS of the pancreas causes the release of the hormone.

Acta Pharmacol Sin. 2004 Feb: 25(2):191-5 Hypoglycaemic effect of Ganoderma lucidum polysaccharides. Shang HN, Lin ZB. Peking University Beijing , China 

 

Pancreatic Beta Cells are protected from damages due to Diabetes

Reishi protects the pancreatic BETA CELLS from alloxan-induced damage that may result in Diabetes.

Alloxan is a toxic compound that is a by-product of bleaching flour and several proteins. It has been strongly linked to the high incidence of Type 1 Diabetes due its ability to destroy the insulin-producing cells of the pancreas.

Reishi protects the pancreatic beta cells from the free radicals produced by Alloxan by neutralizing them with its anti-oxidant polysaccharides.

Life Sci. 2003 Sep 19;73(18):2307-19. In vitri and in vivo protective effects of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage. Zhang HM, Je JH, Yuan L, Lin ZB, Peking University Beijing, China 

 

Clinical Studies on Type 2 Diabetics 

A double-blind, randomized, multicentre study evaluated the efficacy and safety of the Polysaccharide extract of Ganoderma lucidum in 71 patients confirmed with Type II Diabetes Mellitus. Half of the group was given the Reishi extract and the other half received placebo for 12 weeks. After 12 weeks, all of them were evaluated for the signs of change.

After 12 weeks, the group that received the Reishi extract showed SIGNIFICANT reduction of their  glycosylated haemoglobin A1c, fasting and plasma glucose levels while the group that received the placebo  had NO CHANGE or even a slight increase in all the parameters tested. The extract was also well  tolerated.

Int J Med Mushr 2004, 6(1):30-8 A Phase I/II Study of Ling zhi Mushroom Extract in Patients with Type II
Diabetes Mellitus Gao Y, New Zealang; Land J, Dai X, Ye J, China; Zhou S, Singapore

 

 REISHI AND DIABETIC COMPLICATIONS

 

Prevention of Diabetic Kidney complication

Reishi prevents or delays the progression of the renal of kidney complications of diabetic mice.

 Reishi was able to REDUCE the serum Creatinine and Blood Urea Nitrogen levels, two of the most common tests for kidney functionality, as well as the blood glucose and triglycerides of Diabetic Mice.

J Asian Nat Prod Res. 2006 Dec; 8(8):705-11 Effect of polysaccharides from Ganoderma lucidum on streptozotocin-induced diabetic nephropathy in mice. He CY, Li WD, Guo SX, Lin SQ, Lin ZB. Peking  University Beijing, China.

 

 Prevention of Eye and Nerve complications

Glucose in high levels in the blood stream is converted to SORBITOL by the enzyme Aldose reductase. 
 
Sorbitol is a form of glucose that the body cannot use but that attracts a lot of water. Where ever it accumulates, Sorbitol induces damage due cellular swelling.

In the eyes, Sorbitol results in cataracts and retinal damage. In other parts of the body, they cause nerve damage as well blood flow obstruction.

Reishi BLOCKS the enzyme called Aldose reductase and prevents it from converting glucose into sorbitol on the lens of the eyes of diabetic mice. Furthermore, this study also showed the Reishi inhibits the  accumulation of glucose and its by-product sorbitol in the lens, the red blood cells as wells as the sciatic  nerves of diabetic rats. These results suggested that Reishi might possess constituents with antidiabetic and inhibitory effects on diabetic complications.

Phyto Res. 2005 Jun;19(6):477-80. Inhibitory effects of Ganoderma applanatum in rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. Juing SH, Lee YS, Shim SH, Shin KH< Kim JS, Kand SS. Seoul National University, Seoul, Korea

Ganoderma Benefits on Diabetes (Testimonial)

Felisa Gatchalian-Lalas of the Philippines, at age 61, lost her leg when it was too late to discover that she had Diabetes. She was devastated and felt no hope until she was introduced to DXN's Ganoderma products. First she took two pairs of RG/GL together with 3in1 coffee and Spica tea in the first week. It was when she noticed she was gaining strength. She increased the dosage by another two pairs the second week and kept it for a month. Her husband used to piggy back her while going up and down the stairs but eventually she was able to do the flight of stairs on her own. People who knew her were astounded be her fast recovery. Even with a prosthetic leg, and at her age, she is seen by her friends out and about doing her errands. Her son, a medical doctor, was also surprised at her recovery and advised her to keep doing what she was doing.

Story is taken from DXN Philippine’s website

Other Testimonials:

1) Mrs. Vasanthy Narasimhan - 50 years (Referred by Dr.Malathi Ramani) - Known diabetic for 13 years (Insulin dependent). Peripheral neuropathy.  Also had General weakness, breathlessness, chronic fatigue syndrome.  Advised to start on RG + GL as a supportive therapy from May 2000.  First week 1 pair and 2nd week, 2 pairs. Continuous monitoring done.  Same dosage and Lingzhi coffee was also advised to give energy. Patient started improving within 6 months of therapy. On 31.01.2001, she had impairment of blood circulation in both feet, and had frequent ulceration on her big toe, for which RG powder was advised to be applied after cleaning.  Now general health improved.  Blood sugar fluctuating between 130-150.  Dosage of insulin reduced to 10 units.  Cardiac system functioning good.  No burning feet problem.  Patint able to do all her work, by herself.  Ulceration of the toes - healed completely.

2) Mr. Shrinath Dinkar Surkund - Known diabetic for 12 years (Insulin dependant), Acidity, constipation, stress. Started consumption on 01.03.2002 (sugar fasting 248 post lunch 351) RG+GL pair 1 in the morning for 15 days + Morinzhi 2 times a day.  After 15 days, 1 pair morning  and 1 pair in the night + Morinzhi 2 times a day.  Dose continued till Sept 2002.  Insulin 84 units, Glynase Plain, Piozon 15, Glycomet 500.  Sugar level fasting 98 post lunch 120 since April 2002.  Insulin stopped since september 2002.  Glynase plain + Glycomet 500 continued for precaution.  1 pair morning , morinzhi 2 times continued.  Now symptoms controlled.  Good relief from acidity, constipation, stress and can sleep well.

3) Mr. R.Ramasamy (82 years) - Chronic diabetic for the past 17 years and also affected by eczema (skin disease) for the past 7 years. After intake of 3 pairs for 2 months, sugar level came to normal (i.e from 250 to 120 in fasting),. My eczema problem totally vanished and feel very energetic.  Presently continuing with 2 pairs for maintaining my good health.  Remarks :  I am very grateful to my son Mr.K.R.Velusamy and Mr.R.Radhakrishnan for advising me to use this product.

4) Mr. Seram Krishnachoron Singh, 36 years. - Found to be diabetic.  Ganotherapy started on 15th Feb 2002.  First week 2 pairs, 3 pairs from 2nd week and now free from the troubles.  Even though sugar level has increased slightly between 21.02.2002 and 08.03 2002, feel very energetic, can work normally. At present, consuming 3 pairs daily.  Now I  agree the very effectiveness of DXN products RG & GL.  May DXN explore the globe for healthy mission. 

5) Mrs. M. Premavathy - Known diabeties for 15 years with  minor kidney problem.  Taken oral tablets for diabeties for 13 years.  Have become insulin dependent from 1998 onwards.  Severe back pain for several years.  Started ganotherapy on 14.11.2001.  2 pairs of RG& GL and Morinzhi one teaspoon   First three months sugar level has reduced from 325 mg to 250 for fasting and 450 to 325 for post prandiat.  Serium creatine reduced from 1.7 to 1.3 and strict diet control and daily walking.  Sugar level reading as on 25.12.2002  -Fasting 160 mg, Post prandial - 180 mg, serium craeting 1.01. Insulin dosage reduced and oral tables also reduced by 40%.  Able to walk nearly 4 kms every day without any problems.  Presently taking 2 pairs in the morning and 1 pair in the night. 

6) Mrs. K.Rajamma, UAE - I was not fully convinced when it was introduced to me.  As my mother was a diabetic patient for the last 30 years with insulin intake.  I had started giving her 2 pairs as well as two table spoon of Morinzhi two times daily.  With in few days itself, I could see some result in her overall health, and in the 7th month, the sugar level has started coming down.  Today after 16 months, her sugar level is normal and she is not using insulin also.  The same thing has happened to me also, I was diabetic patient for the last 20 years.  When I starated with Ganoderma my sugar level was 425 mg fasting.  I have started with 2 pairs and Morinzhi two table spoon morning and evening and blank coffee also.  Within 5 months my blood sugar level has come down to 90 to 100 mg - fasting.  Both of us are now taking one spoon of mushroom powder daily as a maintenance dosage.  As DXN has come to UAE, I am spending my leisure time to promote ganoderma with the sole intention of helping people by giving them this divine product.  

7) Mr.D.Raveendran, 53 years - I was suffering from blood sugar for the last 17 years and high BP for the last 7 years.  DXN mushroom powder was introduced to me in the month of Dec 2002.  At that time, my blood sugar was 195 mg- fasting and BP 100-170.  I ws using one spoon of mushroom powder daily.  In the month of Feb 2003 when I checked my sugar level, I was surprised to see that it has come down to 147 mg fasting and similar effect was there in my BP level also, it came down to 90-150.  More over my body pain due to improper blood circulation has also came down.

8) Sopiah Bt Hamidul - Malaysia - I was diagnosed with diabetes in March 2000. Subsequently, I injured my foot and it sweled up, got infected with pus and emitted an unpleasant odour, so I had to bandage it. Having gangrene in my foot was an unpleasant experience. I tried countless treatments, but to no avail. Finally, one of my toes was amputated and I gave up hope. I started consuming Ganoderma. A week passed, pus and a fluid discharge oozed from the gangrene and I felt dizziness and pain. With patience and support from family, I continued using the products. My foot slowly healed. There was no more pain and new tissues started to grow. After 2 months, the wound was fully healed. I wish to express my sincere thanks to those who recommended me Ganoderma products and supported me. Today, I can resume with my business activities freely.

9) Mrs. Marzianah Binti Abdul Malik - Malaysia -  During the 7th month of my pregnancy, doctor had a blood test on me and comfirmed that my blood sugar level was as high as 13.75mg/dl. I was seriously warned that the fetus in my womb may have to risk its life due to the abnormal high level of my blood sugar. Later, I learnt from Mr. Eddie Chan who is a health food speaker from DXN that the properties of DXN RG & GL and DXN Spirulina borne special effects for both the pregnant women and her fetus. Therefore, I immediately increased the intake of my dosage to 6 pairs for RG & GL daily and 20 tablets for DXN Spirulina daily and of course I also consumed 2 liters of DXN EWS energy water daily.One week later, I turned up by appointment for the next blood test and I was informed by the doctor that my blood sugar level had returned to normal at 4.87mg/dl.  Finally, I had my normal delivery on 6 February 2003. Thank God that my newly born baby was very health and her skin was tender and beautiful.  I wish to take this opportunity to express my most sincere thanks to DXN Marketing Sdn Bhd. for producing such high quality and effective health foods like RG & GL and Spirulina to all DXN distributors. 

10) Mrs. Ninfa Rios - Los Angeles, CA - I have been taking 1 pair a day of the Ganoderma capsules for
4 weeks now. My blood sugar level history is as follows: Before taking the Ganoderma capsules. After taking the Ganoderma capsules: 1st week: 252; 2nd week: 187;  3rd week: 153 and 4th week: 137. This the first time my blood sugar went down to 137 in 13 years ! I’m so excited about the Ganoderma products.

Note: Above Testimonials are taken from Internet with a view to create awareness regarding benefits of DXN Ganoderma.